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Depression Definition

A severe decline in general economic activity in terms of magnitude and/or length.

Gene Abnormalities Implicated In Bipolar Disorder - Sodium, Calcium Imbalances Linked To Manic Depressive Episodes
The largest genetic analysis of its kind to date for bipolar disorder has implicated machinery involved in the balance of sodium and calcium in brain cells. Researchers supported in part by the National Institute of Mental Health, part of the National Institutes of Health, found an association between the disorder and variation in two genes that make components of channels that manage the flow of the elements into and out of cells, including neurons.
Astonishing 52 Percent Of Newly Diagnosed Bipolar Disorder Patients Receive Antidepressant Drugs In First-Line Treatment
Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, finds that an astonishing 52.3 percent of newly diagnosed bipolar disorder patients are prescribed antidepressant drugs first line. The new report entitled Treatment Algorithms in Bipolar Disorder finds that this high preponderance of early-line antidepressant use stems from primary care physician prescribing.
FDA Approves First Generic Divalproex Sodium To Treat Seizures, Migraine Headaches And Bipolar Disorder
The U.S. Food and Drug Administration approved the first generic versions of Depakote delayed-release tablets (divalproex sodium). Depakote is approved by the FDA for the treatment of seizures, bipolar disorder and migraine headaches. "Generic drugs undergo a rigorous scientific review to ensure that they will provide the patient with the same amount of high quality, safe and effective drug as the name brand product," said Gary J.
Depression And Bipolar Results Worth Striving For - A New Recovery Model For Mental Illness
Bipolar Advantage Inc. will be introducing a new integrated recovery program called the "Advantage Program" on September 6, 2008. "The days of thinking a diagnosis of bipolar disorder means living a diminished life are over," says company president Tom Wootton.
Supplemental New Drug Application For Risperdal® Consta® Submitted To The FDA For The Treatment Of Bipolar Disorder
Alkermes, Inc. (NASDAQ: ALKS) today announced that its partner, Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (J&JPRD), submitted a supplemental New Drug Application (sNDA) for RISPERDAL® CONSTA® [(risperidone) Long-Acting Injection] to the U.S. Food and Drug Administration (FDA) for approval as monotherapy in the maintenance treatment of bipolar I disorder to delay the time to occurrence of mood episodes in adults.
Alexza Initiates Second Phase 3 Clinical Trial For AZ-004 (Staccato(R) Loxapine)
Alexza Pharmaceuticals, Inc. (Nasdaq: ALXA) announced that it has initiated its second Phase 3 clinical trial with AZ-004 (Staccato(R) loxapine). AZ-004 is an inhalation product candidate being developed for the treatment of acute agitation in patients with schizophrenia or bipolar disorder.
Improving Traditional Psychiatric Diagnoses With Genetics
Psychiatry has begun the laborious effort of preparing the DSM-V, the new iteration of its diagnostic manual. In so doing, it once again wrestles with the task set by Carl Linnaeus, to "cleave nature at its joints." However, these "joints," the boundaries between psychiatric disorders, such as that between bipolar disorder and schizophrenia, are far from clear. Prior versions of DSM followed the path outlined by Emil Kraeplin in separating these disorders into distinct categories.
Partially Shared Genetic Profile Between Schizophrenia And Bipolar Disorder Discovered
Both schizophrenia and bipolar disorder can be disabling conditions, and both present clinically with significant mood and psychotic symptoms. These two illnesses also share genetic variants that might be involved in the predisposition to both disorders.
Astrazeneca Sponsors Service User- Involvement In Research Into Recovery For Mental Health
Two leading mental health charities, Rethink and MDF The BiPolar Organisation today announced the start of a new partnership with and project sponsored by AstraZeneca. It comprises of experiential research to identify what hinders and helps achieve recovery and aims to help to put recovery at the heart of mental health reform. It will report late 2008.
The ECNP Consensus Statement On Bipolar Depression
Bipolar disorder is one of the most complex and challenging mental disorder in the spectrum. Bipolar disorder is typically associated with considerable acute and longterm treatment needs and may be associated in the course of illness with times of tremendous social burden for both the individual and family. It is typically referred to as an episodic, yet lifelong and clinically severe mood disorder.
New Scholarship For Leaders Of Bipolar Lives
What do you do when you want to let the bipolar community know about scholarships for people with bipolar disorder, but soon discover that support for bipolar students is still far too rare? Why donate a scholarship yourself of course. The Bipolar Lives Scholarship is a new scholarship, created when journalist Sarah Freeman added a webpage on bipolar scholarships to the Bipolar Lives website, but found only a handful of suitable awards existed.
Mental Health Treatment: It's Commonly Accepted Yet Not So Easy To Obtain Or Understand
Seeing a psychologist or other mental health professional isn't an unusual thing; in fact it's relatively common. Nearly three in ten U.S. adults (29%) report that they have received treatment or therapy from a psychologist or other mental health professional. The survey also found that younger adults are more open to seeking mental health treatment than those over 50 and that many adults are not discouraged from seeking treatment because of stigma or fear of others finding out.
Relapse Time Prolonged In Clinically Stable Patients With Bipolar I Disorder Treated With Quetiapine As Adjunct Therapy To Mood Stabilisers
AstraZeneca announced the online publication of long-term SEROQUEL® (quetiapine fumarate) clinical trial data in the Journal of Affective Disorders. Results show that SEROQUEL in combination with lithium or divalproex significantly increased the time to recurrence of any mood event in patients with bipolar I disorder compared with lithium or divalproex alone.
FDA Approves First Generic Risperidone To Treat Psychiatric Conditions
The U.S. Food and Drug Administration approved the first generic versions of Risperdal (risperidone) tablets. Risperdal is an antipsychotic drug used for the treatment of schizophrenia, bipolar disorder, and other psychiatric conditions.
Link Between Poor Sleep And Suicidal Behavior Among Children And Adolescents With Depressive Episodes
A research abstract presented at SLEEP 2008, the 22nd Annual Meeting of the Associated Professional Sleep Societies (APSS), finds a link between poor sleep and suicidal behavior among children and adolescents with depressive episodes. The study, authored by Maria-Cecilia Lopes, MD, PhD, of Sao Paulo University in Brazil, focused on 303 individuals with pediatric bipolar disorder and pediatric unipolar disorder during depressive episodes.
Repligen Announces Plans To Initiate A Phase 2b Trial For RG2417 In Bipolar Disorder
Repligen Corporation (Nasdaq: RGEN) announced that based on feedback from the Food and Drug Administration, the Company plans to initiate a Phase 2b clinical trial of RG2417, an oral formulation of uridine, in patients with bipolar disorder later this year. This will be a multi-center, parallel arm placebo-controlled, clinical trial in which approximately 150 patients with bipolar disorder will receive either RG2417 or a placebo twice a day for eight-weeks.
Antidepressants Alone: Not For Bipolar Depression
Psychiatrists have cautioned against the use of antidepressants alone in people with bipolar disorders, saying they could worsen a patient's condition by causing a destabilisation in mood.
Report Confirms Increased Risk Of Smoking, Substance Abuse In Bipolar Adolescents
A study from the Massachusetts General Hospital (MGH) supports previous reports that adolescents with bipolar disorder are at increased risk for smoking and substance abuse. The article appearing in the June Drug and Alcohol Dependence - describing the largest such investigation to date and the first to include a control group - also indicates that bipolar-associated risk is independent of the risk conferred by other disorders affecting study participants.
NARSAD Researchers Identify Specific Genes And Family Traits Linked To Schizophrenia, Bipolar Disorder And Depression
New findings from research supported by NARSAD, the world's leading charity dedicated to mental health research, and conducted by Harvard-affiliated scientists are providing important clues into how genes work to impair various aspects of attention, memory and perception -- the behaviors associated with many psychiatric illnesses, such as schizophrenia, bipolar disorder and depression.
ABILIFY(R) (aripiprazole) Receives Expanded Indications For Maintenance Treatment In Pediatric Patients With Bipolar Disorder And Schizophrenia
Otsuka Pharmaceutical Co., Ltd. and Bristol-Myers Squibb Company (NYSE: BMY) announced that ABILIFY® (aripiprazole) received expanded indications in Bipolar I Disorder and Schizophrenia. ABILIFY is now indicated for maintenance treatment of manic and mixed episodes associated with Bipolar I Disorder with or without psychotic features in pediatric patients (aged 10-17) and maintenance treatment of Schizophrenia in adolescents (aged 13-17).
FDA Approves Astrazeneca's Seroquel For Maintenance Treatment In Bipolar Disorder
AstraZeneca announced that the U.S. Food and Drug Administration (FDA) has approved SEROQUEL® (quetiapine fumarate) for the maintenance treatment of patients with bipolar I disorder, as adjunct to lithium or divalproex. SEROQUEL is approved by the FDA for the treatment of schizophrenia, and is also the only single agent approved by the FDA for the treatment of both depressive episodes in bipolar disorder and acute manic episodes associated with bipolar I disorder1,2.
Perceptual Switch Rates With Ambiguous Structure-from-motion Figures In Bipolar Disorder
Most people believe that the way we see things is affected by how we feel emotionally. Does our mood really change what we see or do individuals with certain genetic traits always tend to see things differently, regardless of their mood? Earlier research suggested that people with bipolar mood disorder might alternate their perception more slowly when looking at ambiguous figures.
Overview Of Asenapine Data From Olympia Trial Program Presented At American Psychiatric Association Annual Meeting
Schering-Plough Corporation (NYSE: SGP) announced that an overview of asenapine clinical trials from the Olympia program was presented at the 161st Annual Meeting of the American Psychiatric Association in Washington, D.C., May 3-8. Data from the studies, involving patients with bipolar I disorder and schizophrenia, were presented in two oral presentations (Abstracts # 44 and # 80).
Problems Identified With Diagnosis Of Bipolar Disorder
A new study by Rhode Island Hospital and Brown University researchers reports that fewer than half the patients previously diagnosed with bipolar disorder received a diagnosis of bipolar disorder based on a comprehensive, psychiatric diagnostic interview - -the Structured Clinical Interview for DSM-IV (SCID).
Benefits Of Omega 3s Still Unclear For Bipolar Disorder
Despite intriguing findings that omega 3 fatty acid supplements could alleviate depression symptoms, there is still not enough evidence to say whether omega 3s are useful treatments for people with bipolar disorder, according to a review of recent studies.

Online Depression Screening Test guide

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One of the mood conditions that affect how you think, feel and behave is depression. Jobs, family and society in general are all affected by the abnormal functioning during depression. You may feel powerless incapable of dealing with your life, including thoughts, feelings and behavior. Lingering sometimes for years, permanent disability can be caused by untreated depression. A lack of enjoyment in previously enjoyed activities is one symptom of and feelings of worthlessness are another.

Different people have different symptoms and the same person may experience different symptoms over time. A person may experience one, several or all symptoms during a depressed state. Long-term, minor that keeps a person from feeling well is called dysthymia. A lighter mood results from medication, thus enabling you to work on problems. Medication that restores the balance of neurotransmitters is the treatment for depression.

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Medication has become the first method of treatment as it can relieve symptoms of depression. A professional is able to assist you in getting whatever help you need. Essential to alleviating feelings of exhaustion and weakness is support from others. Having someone as a sounding board is therapeutic for a number of people. A concerned family can make a difference by offering encouragement and support.

Recovery can be promoted additionally by peer education and support. Symptoms of can be alleviated,

Depression and Disability Benefits - SSI and SSDI
Even with the best of treatment and the best possible support system, depression, other mental health conditions, and comorbid conditions can sometimes be quite debilitating.   Health issues make life difficult enough without the added burden of being unable to work and support oneself. If you find yourself in this situation, there are disability benefits you may want to investigate. The Social Security Disability Insurance (SSDI)...
Have a Mental Illness? Don't Plan on Attending the Beijing Olympics.
Sad and angry? Yes. Surprised? No. That's my basic reaction to a nine-page document issued by the Beijing Olympic organizing committee.   The document lists who will be denied a visa and entry to China for the Olympics. That list includes those with "mental diseases."   Ironically, China has lifted a longstanding rule that banned people with leprosy from entering the country. A government official stated, "The reason...
Depression Interview on the Radio Saturday
If you're in the Waco, Texas, area...   Check out "Lessons for Your Life" on 94.5 FM radio Saturday morning at 8:30 a.m. (central time)   It was my pleasure to talk with the show's host, Robert Barnes, for nearly an hour yesterday afternoon. Our discussion will be broken into two radio shows airing on Saturday mornings. Our discussion covered: What is the difference between feeling down and major depressive disorder? When do we...
YES! House Passes Increases for Veterans Mental Illness Treatment
I just received a NAMI email newsletter that contains great news about treatments for our veterans... By a vote of 409-4 the House today passed legislation funding the Department of Veterans Affairs for FY 2009. The bill (HR 6599) includes $3.8 billion for mental illness treatment and $584 million for substance abuse treatment in the VA, significant increases over current year funding. Overall, the Veterans Health Administration budget is set...
Viagra for Women's Depression
It's possibly the most highly advertised and discussed medication in the history of the pharmaceutical industry. It's that "little blue pill," Viagra.   A July JAMA article reports on a study testing Viagra (sidenafil) to offset the sexual dysfunction side effects of selective serotonin reuptake inhibitor and nonselective serotonin reuptake inhibitor antidepressants (SRIs). Other studies have suggested that Viagra may be effective for...
Coping with Depression - Does Spirituality Help?
A blog carnival I follow came out this week on the topic, 'How Spirituality Helps Us Cope with Migraine Disease." It made me think not only about the Migraines I have, but also about how I cope with depression.   Yes, I take an antidepressant, but that's not really enough for me to feel my best. Plus, even with the medication, I have those days when I want to just go back to bed, those days when I sit at my computer all day but can't seem...
Treatment Helpful in Reducing Risk of Depression After Stroke
A study in the May 28 issue of JAMA reports that in the year following a stroke, patients who received the medication escitalopram (Lexapro) or participated in a problem-solving therapy group had a lower risk of depression compared to patients who received placebo.   The authors of the JAMA article state,   "Post-stroke depression has been shown in numerous studies to be associated with both impaired recovery in activities of daily...
Watch <i>Depression: Out of the Shadows</i> Online
If you missed Wednesdays broadcast of Depression: Out of the Shadows on PBS, or if you'd like to see it again, there's good news! It's now available on the PBS web site. You can watch it online, read the transcript, or purchase a copy of the video. Just visit THIS PAGE on the PBS site.
5/21 - Depression: Out of the Shadows - A Progam You'll Want To Watch
Public awarness and understanding of depression is sorely lacking. Because of this, too many of us still feel the stigma of depression. Family, friends, and employers often just "don't get it."   Tomorrow, May 21, Depression: Out of the Shadows airs on PBS. Here are some quotes from the documentary: I wish I could answer why this is happening..." "If you think about the worst you have ever felt in your life and imagine feeling...
Depression Tied To Increased Risk of Alzheimer's Disease
According to a study published in the April 8, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology, people who have had depression are more likely to develop Alzheimer's disease (AD) than people who have never had depression. Study author Dr. Monique M.B. Breteler, with the Erasmus University Medical Center in the Netherlands, commented,"We don't know yet whether depression contributes to the...

and even eliminated, by treatments such as antidepressant medication and psychotherapy. Additional study is needed on the other available methods that a number of people have used effectively. Not only do things like type and severity of play into treatment success, but also things like length of illness and personal reaction. Physical exams normally precede any type of treatment for clinical depression.

Being down in the dumps or in a poor mood isn't depression. Medical conditions such as heart disease, diabetes and affect all aspects of your daily life. can be treated successfully by a professional despite its seriousness.

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Little is understood about the conceptual relationship of and quality of life (QoL).

Clinical affects about 7% - 18% of the population on at least one occasion in their lives, before the age of 40.

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